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Results for " HY-132588 " in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Area
  • HY-132588
    Lumasiran Small Interfering RNA (siRNA) Metabolic Disease
    Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[1][2].

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